This case study explores the role of public art—specifically environmental murals—as a culturally resonant medium for health communication in low-resource contexts. Centered in Malawi, the project highlights collaborations between students in an Indigenous Knowledge Systems and Practices program and local public hospitals to design and implement murals promoting maternal and infant health. By blending traditional storytelling methods with visual communication strategies, the murals support community health education in a way that is accessible, engaging, and rooted in local cultural values. Aligned with the theme “Where Legacy Meets Future,” this work bridges ancestral knowledge and contemporary health challenges, offering a model for interdisciplinary, socially embedded design education. It expands the scope of industrial design by demonstrating how participatory visual practices can inform public health while fostering deeper community engagement.